DNA Binding Site
| Accessions: | 3p57_E (3D-footprint 20231221), 3p57_G (3D-footprint 20231221), 3p57_K (3D-footprint 20231221), 6byy_K (3D-footprint 20231221) |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 14 |
| Sequence: | AACTATTTATAAGA |
| Type: | Heterodimer |
| Binding TFs: | 3p57_B / 3p57_D / 3p57_J (SRF-type transcription factor (DNA-binding and dimerisation domain)) 6byy_B (SRF-type transcription factor (DNA-binding and dimerisation domain)) |
| Binding Motifs: | 3p57_AB TAnnnnTAG 3p57_CD CTannnntAA 3p57_IJ CTAnnnnTAA 6byy_AB TAnnnnTAG |
| Publications: | He J, Ye J, Cai Y, Riquelme C, Liu J.O, Liu X, Han A, Chen L. Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly. Nucleic acids research 39:4464-74 (2011). [Pubmed] Lei X, Kou Y, Fu Y, Rajashekar N, Shi H, Wu F, Xu J, Luo Y, Chen L. The Cancer Mutation D83V Induces an α-Helix to β-Strand Conformation Switch in MEF2B. J Mol Biol 430:1157-1172 (2018). [Pubmed] |
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