DNA Binding Motif

						

			
Accessions: 3p57_CD (3D-footprint 20231221)

			
Names: Myocyte-specific enhancer factor 2A
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA
Length: 10
Consensus: CTannnntAA
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02      0      0      0     96      T
03     54     16     13     13      a
04     24     24     24     24      n
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08     13     16     13     54      t
09     96      0      0      0      A
10     96      0      0      0      A
Binding TFs: 3p57_C / 3p57_D (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 3p57_G
3p57_H
			
Publications: He J, Ye J, Cai Y, Riquelme C, Liu J.O, Liu X, Han A, Chen L. Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly. Nucleic acids research 39:4464-74 (2011). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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