DNA Binding Motif

						

			
Accessions: 3p57_AB (3D-footprint 20231221)

			
Names: Myocyte-specific enhancer factor 2A
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA
Length: 9
Consensus: TAnnnnTAG
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02     76      9     11      0      A
03     24     24     24     24      n
04     24     24     24     24      n
05     24     24     24     24      n
06     24     24     24     24      n
07     11      9      9     67      T
08     86      0     10      0      A
09      9      9     69      9      G
Binding TFs: 3p57_A / 3p57_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 3p57_E
3p57_F
			
Publications: He J, Ye J, Cai Y, Riquelme C, Liu J.O, Liu X, Han A, Chen L. Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly. Nucleic acids research 39:4464-74 (2011). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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