DNA Binding Motif

Accessions: 3p57_IJ (3D-footprint 20231221)
Names: Myocyte-specific enhancer factor 2A
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA
Length: 10
Consensus: CTAnnnnTAA
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 0 0 0 96 T
03 67 11 9 9 A
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 9 11 9 67 T
09 96 0 0 0 A
10 67 9 11 9 A
Binding TFs: 3p57_I / 3p57_J (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 3p57_K
3p57_L
Publications: He J, Ye J, Cai Y, Riquelme C, Liu J.O, Liu X, Han A, Chen L. Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly. Nucleic acids research 39:4464-74 (2011). [Pubmed]

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