DNA Binding Site

Accessions: TTAATAAA (UniPROBE 20160601), MA2158.1.13 (JASPAR 2024), MA2158.1.18 (JASPAR 2024)
Organisms: Mus musculus, Saccharomyces cerevisiae, Homo sapiens, Caenorhabditis elegans
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: TTAATAAA
Type: Heterodimer
Binding TFs: UP00012A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
UP00188A (Homeobox domain, Homeobox KN domain)
UP00294A (SRF-type transcription factor (DNA-binding and dimerisation domain))
UP00597B (Homeobox domain)
UP00597D (Homeobox domain)
UP00597G (Homeobox domain)
UP00627B (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00627C (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00627D (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00627E (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00627G (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
P20271
Binding Motifs: UP00012A_1 taaTTCAwTGAAswd
UP00188A_1 sgawTTAATTAAwwwyy
UP00294A_1 tkacctwtAATTawaybwsmw
UP00012A_2 tvwybGTTAACaswkrr
UP00597B_1 tksmrytyaATAAAAwwcdmtt
UP00597D_1 tkswwyyyaATAAAAwwcmmtt
UP00597G_1 wwtaaryYAATAAAAwtcwmww
UP00597G_2 wrkmrayYAATAAAAwwcwmtt
UP00627B_1 TwtTwawATAmAwATAAwwTwkG
UP00627C_1 TwtTwawATAmAwATAAwwThkG
UP00627D_1 kwtwywwCCCCCGCAyrwkyww
UP00627E_1 gassrATGCGkGGGAwrdkwwa
UP00627G_1 TwtTtawATAmAwATAAwwThkG
MA2158.1 tTAATTAa
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

Kagoshima H, Kohara Y. Co-expression of the transcription factors CEH-14 and TTX-1 regulates AFD neuron-specific genes gcy-8 and gcy-18 in C. elegans 399:325-36 (Dev). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.