Transcription Factor

Accessions: UP00294A (UniPROBE 20160601)
Names: Smp1, Transcription factor SMP1, YBR1245, YBR182C
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P38128
Description: Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors
Length: 108
Pfam Domains: 8-58 SRF-type transcription factor (DNA-binding and dimerisation domain)
Sequence:
(in bold interface residues)
1 GRRKIEIEPIKDDRNRTVTFIKRKAGLFKKAHELSVLCQVDIAVIILGSNNTFYEYSSVD 60
61 MSNLLNVHQNNTDLPHNIIEPSDYGDYVKKPRVVLNERKRRRRRATVL
Interface Residues: 2, 3, 14, 17, 18, 22
3D-footprint Homologues: 1n6j_A, 1c7u_A, 7x1n_C, 1hbx_A, 1mnm_A
Binding Motifs: UP00294A_1 tkacctwtAATTawaybwsmw
Binding Sites: AAAATAGA
AAATTAAT
AATATATT
AATTAATA
AATTAATT
ATAAATTA
ATATATTA
ATATTAAG
ATTAATAA
ATTAATTA
CTAATATA
TAAATTAA
TAATATAA
TAATATTA
TAATTATA
TAATTTAA
TATATTAA
TATTAATA
TTAATAAA
CCCACCCG
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]
Related annotations: PaperBLAST

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