DNA Binding Motif
| Accessions: | UP00627E_1 (UniPROBE 20160601) |
| Names: | AWT1, GUD, NPHS4, WAGR, Wilms tumor protein, WIT-2, WT1_R366L_R1, WT33 |
| Organisms: | Homo sapiens |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 22 |
| Consensus: | gassrATGCGkGGGAwrdkwwa |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.24 0.22 0.32 0.22 g 02 0.60 0.15 0.09 0.16 a 03 0.15 0.42 0.27 0.16 s 04 0.23 0.28 0.29 0.20 s 05 0.39 0.10 0.38 0.14 r 06 0.68 0.03 0.24 0.05 A 07 0.03 0.08 0.01 0.89 T 08 0.05 0.01 0.94 0.01 G 09 0.01 0.79 0 0.19 C 10 0.01 0 0.98 0.01 G 11 0.01 0 0.64 0.35 k 12 0.03 0 0.96 0 G 13 0.01 0 0.99 0 G 14 0.02 0 0.93 0.05 G 15 0.75 0.10 0.06 0.09 A 16 0.29 0.05 0.08 0.59 w 17 0.34 0.06 0.42 0.17 r 18 0.29 0.10 0.27 0.34 d 19 0.22 0.14 0.37 0.28 k 20 0.28 0.18 0.14 0.39 w 21 0.38 0.23 0.08 0.31 w 22 0.37 0.22 0.19 0.22 a |
| Binding TFs: | UP00627E (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger) |
| Binding Sites: | TAATAAAA AACAATAT AATAAAAT AATATTAA ATAAAATA ATATTATG CCCACGCA CCCCCGCA GCGGGGGA GCGTGGGA TTAATAAA AATTTATA ACATACAT ACATATAA ATAATACA ATATAAGA ATATTTAA ATGTATTA TACATATA TATTTCAA |
| Publications: | Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed] |
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