DNA Binding Motif

Accessions: UP00422A_1 (UniPROBE 20160601)
Names: AI414410, ETS domain transcriptional repressor PE1, ETS translocation variant 3, ets variant gene 3, ETS-domain transcriptional repressor, Etv3, Mets, Mitogenic Ets transcriptional suppressor, PE-1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: rygaAyTTCCGGtaky
Weblogo:
PSSM: P0 A C G T
01 0.33 0.23 0.27 0.16 r
02 0.14 0.36 0.21 0.29 y
03 0.18 0.23 0.36 0.23 g
04 0.41 0.22 0.14 0.23 a
05 0.75 0.02 0.19 0.04 A
06 0 0.49 0.02 0.48 y
07 0.09 0 0.01 0.89 T
08 0.01 0 0 0.99 T
09 0 0.99 0 0 C
10 0 0.99 0 0 C
11 0 0.01 0.94 0.05 G
12 0.10 0.06 0.80 0.03 G
13 0.24 0.09 0.06 0.61 t
14 0.44 0.18 0.16 0.22 a
15 0.21 0.14 0.38 0.26 k
16 0.21 0.33 0.18 0.28 y
Binding TFs: UP00422A (Ets-domain)
Binding Sites: AACTTCCG
ACATCCGG
ACCGGAAA
ACCGGAAG
ACCGGATG
ACTTCCGA
ACTTCCGG
ATCCGGAA
ATCCGGAT
CACCGGAA
CACTTCCG
CATTTCCG
CCGGAAAC
CCGGAAGC
CCGGATGC
CGGAAACA
CGGAAATA
CTTCCGGA
TCCGGAAA
TTCCGGAA
Publications: Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]

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