Transcription Factor
| Accessions: | UP00422A (UniPROBE 20160601) |
| Names: | AI414410, ETS domain transcriptional repressor PE1, ETS translocation variant 3, ets variant gene 3, ETS-domain transcriptional repressor, Etv3, Mets, Mitogenic Ets transcriptional suppressor, PE-1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q8BN37 |
| Description: | ets variant gene 3: ETS translocation variant 3 |
| Length: | 117 |
| Pfam Domains: | 16-99 Ets-domain |
| Sequence: (in bold interface residues) | 1 FPDWAYKAESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGR 60 61 RKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVMPNYPFINIRSSGV |
| Interface Residues: | 14, 34, 38, 70, 71, 73, 74, 75, 77, 78, 80, 81, 83, 84, 89, 92, 93, 95, 96 |
| 3D-footprint Homologues: | 3zp5_A, 5f0q_A, 7jsa_J, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 8ee9_F, 1dux_F, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C, 4l18_B, 8d0k_E |
| Binding Motifs: | UP00422A_1 rygaAyTTCCGGtaky |
| Binding Sites: | AACTTCCG ACATCCGG ACCGGAAA ACCGGAAG ACCGGATG ACTTCCGA ACTTCCGG ATCCGGAA ATCCGGAT CACCGGAA CACTTCCG CATTTCCG CCGGAAAC CCGGAAGC CCGGATGC CGGAAACA CGGAAATA CTTCCGGA TCCGGAAA TTCCGGAA |
| Publications: | Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
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