Transcription Factor
| Accessions: | UP00414A (UniPROBE 20160601) |
| Names: | 5\' domain, AI196000, AI448617, D230050P06, E26 avian leukemia oncogene 1, Ets-1, Ets1, MGC130355, MGC18571, p42Ets-1, p51Ets-1, p54, Protein C-ets-1, Tpl1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P27577 |
| Description: | E26 avian leukemia oncogene 1, 5\' domain: protein C-ets-1 isoform 1 |
| Length: | 116 |
| Pfam Domains: | 17-98 Ets-domain |
| Sequence: (in bold interface residues) | 1 PVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKR 60 61 KNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLD |
| Interface Residues: | 14, 47, 51, 52, 55, 69, 70, 72, 73, 74, 76, 77, 91 |
| 3D-footprint Homologues: | 3zp5_A, 2wbs_A, 4uno_A, 3jtg_A, 7jsa_J, 2stt_A, 8ee9_F, 4mhg_A, 1dux_F, 4l18_B, 1yo5_C, 1awc_A, 4lg0_B, 4bqa_A, 1bc8_C, 4iri_A |
| Binding Motifs: | UP00414A_1 crkkyACCGGAArtaaw |
| Binding Sites: | AACCGGAA ACATCCGG ACCGGAAA ACCGGATA ACCGGATG ACTTCCGC ACTTCCGG AGCGGAAG ATATCCGG ATTTCCGG CACCGGAA CATCCGGC CATTTCCG CCGGAAAC CCGGAAGC CCGGATGC CTTCCGGC GCCGGAAA TACCGGAA TTCCGGAA |
| Publications: | Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed] |
| Related annotations: | PaperBLAST |
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