Transcription Factor
| Accessions: | UP00281A (UniPROBE 20160601) |
| Names: | Putative 82.2 kDa transcriptional regulatory protein in FRE2 5'region, Ykl222c |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P35995 |
| Description: | Putative protein of unknown function; similar to transcriptional regulators from the zinc cluster (binuclear cluster) protein family; null mutant is sensitive to caffeine |
| Length: | 110 |
| Pfam Domains: | 21-57 Fungal Zn(2)-Cys(6) binuclear cluster domain |
| Sequence: (in bold interface residues) | 1 KNTELSQKKKLDRQSRRKPAKSCHFCRVRKLKCDRVRPFCGSCSSRNRKQCEYKENTSAM 60 61 EDQLRKKYRRCSKLEMARRIEELESQLTKQSQPNIHEGQNPLSNMRYLSS |
| Interface Residues: | 29, 30, 31 |
| 3D-footprint Homologues: | 1hwt_C, 1pyi_A, 1zme_D, 1d66_B, 3coq_A, 6gys_C, 7uik_T |
| Binding Motifs: | UP00281A_1 mssabmrCGGArATwasdsgk |
| Binding Sites: | AACGGAAA AACTCCGG AACTCCGT AATTCCGT ACGGAAAT ACGGAGAT ACGGGAAT ATCTCCGC ATGTCCGC ATTTCCGC ATTTCCGG CACGGAAA CGGAAATA CGGAGATA CGGGAATA TCCGCGGA AAATCCGT AACGGGAT AATCCCGT ATTCCGTC |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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