Transcription Factor

Accessions: Q12951 (JASPAR 2024)
Names: Forkhead box protein I1, Forkhead-related protein FKHL10, Forkhead-related transcription factor 6, FOXI1_HUMAN, FREAC-6, Hepatocyte nuclear factor 3 forkhead homolog 3, HFH-3, HNF-3/fork-head homolog 3
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q12951
Length:
Binding Motifs: MA0042.2 GTAAACA
UN0496.1 AsCGGAArTrTmAACAk
UN0497.1 rCCGGAAGsWmArCAk
MA1935.1 rtaaACmGGAArtr
MA1946.1 GtMAACMGGAwGy
MA0042.1 ksdTrTTTrTwT
MA1935.2 aaACmGGAAr
MA1946.2 GtMAACMGGAwG
UN0496.2 AsCGGAArTrTmAACA
Publications: Overdier D. G., Ye H., Peterson R. S., Clevidence D.E., Costa R. H. The winged helix transcriptional activator HFH-3 is expressed in the distal tubules of embryonic and adult kidney. J. Biol. Chem. 272:13725-13730 (1997). [Pubmed]

Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed]

Ibarra IL, Hollmann NM, Klaus B, Augsten S, Velten B, Hennig J, Zaugg JB. Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions. Nat Commun 11:124 (2020). [Pubmed]
Related annotations: PaperBLAST

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