DNA Binding Motif

						

			
Accessions: ELK1_FOXI1_2 (HumanTF2 1.0), UN0497.1 (JASPAR 2024)

			
Names: ELK1_FOXI1, ELK1::FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 16
Consensus: rCCGGAAGsWmArCAk
Weblogo: 
PSSM: P0      A      C      G      T
01    512      0    531     10      r
02    116    793    251      0      C
03      0   1043      0      7      C
04      0      0   1043     23      G
05    176      0   1043      0      G
06   1043      4      0     36      A
07   1043      0      4     35      A
08     14    252    741     36      G
09    183    607    860     18      s
10    304      5     17    739      W
11    672    371      0      9      m
12   1043     32     22      0      A
13   1043     13    528      0      r
14      0   1043      0    170      C
15   1043     18      1    211      A
16    251      2    340    450      k
Type: Heterodimer
Binding TFs: Q12951 (Fork head domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
FOXI1_TF2 (Fork head domain)
ELK1_TF1 (Ets-domain)
Q12951
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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