Transcription Factor

Accessions: UP00015A (UniPROBE 20160601), UP00403A (UniPROBE 20160601)
Names: 9030625L19Rik, AU019492, Ehf, ets homologous factor
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q922E8
Description: ets homologous factor: Mus musculus EHF (Ehf) mRNA, complete cds
Length: 110
Pfam Domains: 17-100 Ets-domain
Sequence:
(in bold interface residues)
1 QDHPVKSHTKKHNPRGTHLWEFIRDILLSPDKNPGLIKWEDRSEGIFRFLKSEAVAQLWG 60
61 KKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN
Interface Residues: 71, 72, 74, 75, 76, 78, 79, 93
3D-footprint Homologues: 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C, 4l18_B
Binding Motifs: UP00015A_1 mkdwcsCGGAARtwa
UP00403A_1 smyswryTTCCGGsttk
UP00015A_2 wwrkAkTTCCkAwsww
Binding Sites: AACTTCCG
AACTTCCT
AAGGAAGT
ACCCGGAA
ACGGAAGT
ACTTCCGC
ACTTCCGG
ACTTCCTG
AGGAAGTA
ATTTCCGC
CACTTCCG
CCCGGAAA
CCCGGAAG
CCGGAAAC
CCGGAAGC
CGGAAGTA
CTTCCGGA
CTTCCGGC
GGAAGTAA
TTCCGGAA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.