Transcription Factor

Accessions: UP00032A (UniPROBE 20160601)
Names: GATA binding protein 3, Gata-3, GATA-binding factor 3, Gata3, Trans-acting T-cell-specific transcription factor GATA-3
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: GATA binding protein 3: Mus musculus GATA binding protein 3 (Gata3), mRNA.
Length: 135
Pfam Domains: 22-55 GATA zinc finger
76-108 GATA zinc finger
Sequence:
(in bold interface residues)
1 SPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLI 60
61 KPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGI 120
121 QTRNRKMSSKSKKCK
Interface Residues: 31, 32, 34, 44, 48, 85, 86, 88, 98, 102, 103, 106, 123, 125, 126
3D-footprint Homologues: 4hc9_A, 3vd6_C, 3dfx_B, 1gat_A, 4gat_A
Binding Motifs: UP00032A_1 bkwdwakAGATAAGArwtdarg
UP00032A_2 ytwtrywGATtktATCrrbwhm
Binding Sites: AGATAACA
AAAGATAA
AAGATAAG
ACTGATAA
AGAGATAA
AGATAACG
AGATAAGA
AGATAAGC
AGATAAGG
ATCTTATC
CAGATAAG
CGAGATAA
CGATAAGA
CTCTTATC
CTGATAAG
CTTATCTA
CTTATCTC
GAGATAAC
GATAAGAA
TCTTATCA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.