DNA Binding Site
| Accessions: | MA1123.3.19 (JASPAR 2024), MA1472.3.4 (JASPAR 2024), MA1619.2.3 (JASPAR 2024), MA1641.2.13 (JASPAR 2024), MA2295.1.11 (JASPAR 2024), MA2295.1.3 (JASPAR 2024), UN0733.1.17 (JASPAR 2024) |
| Organisms: | Homo sapiens, Mus musculus, Drosophila melanogaster, Caenorhabditis elegans |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | CCAGCTGT |
| Type: | Heterodimer |
| Binding TFs: | Q9QYC3 (Helix-loop-helix DNA-binding domain) Q9QX98 (Helix-loop-helix DNA-binding domain) Q15672 (Helix-loop-helix DNA-binding domain) P13349 (Helix-loop-helix DNA-binding domain, Myogenic Basic domain, Myogenic determination factor 5) P10083 P13349 Q11094 Q15672 Q9QX98 Q9QYC3 |
| Binding Motifs: | MA1123.3 CCAGATGt MA1472.3 ACAGCTGT MA1619.2 aCAGCTGt MA1641.2 aCAGCTGt MA2295.1 gCAGCTGc UN0733.1 cCAGmTGg |
| Publications: | Shukunami C, Takimoto A, Nishizaki Y, Yoshimoto Y, Tanaka S, Miura S, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y. Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes. Sci Rep 8:3155 (2018). [Pubmed] Lo HG, Jin RU, Sibbel G, Liu D, Karki A, Joens MS, Madison BB, Zhang B, Blanc V, Fitzpatrick JA, Davidson NO, Konieczny SF, Mills JC. A single transcription factor is sufficient to induce and maintain secretory cell architecture. Genes Dev 31:154-171 (2017). [Pubmed] Meredith DM, Borromeo MD, Deering TG, Casey BH, Savage TK, Mayer PR, Hoang C, Tung KC, Kumar M, Shen C, Swift GH, Macdonald RJ, Johnson JE. Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility. Mol Cell Biol 33:3166-79 (2013). [Pubmed] Conerly ML, Yao Z, Zhong JW, Groudine M, Tapscott SJ. Distinct Activities of Myf5 and MyoD Indicate Separate Roles in Skeletal Muscle Lineage Specification and Differentiation. Dev Cell 36:375-85 (2016). [Pubmed] Nitta KR, Jolma A, Yin Y, Morgunova E, Kivioja T, Akhtar J, Hens K, Toivonen J, Deplancke B, Furlong EE, Taipale J. Conservation of transcription factor binding specificities across 600 million years of bilateria evolution. Elife : (2015). [Pubmed] |
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