DNA Binding Site

Accessions: 2han_D (3D-footprint 20231221), 4umm_D (3D-footprint 20231221)
Organisms: Drosophila melanogaster, Heliothis virescens, Tobacco budworm moth
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 19
Sequence: ACAAGTGCATTGAACCCTT
Type: Heterodimer
Binding TFs: 2han_A (Zinc finger, C4 type (two domains))
2han_B (Zinc finger, C4 type (two domains))
4umm_E (Zinc finger, C4 type (two domains))
Binding Motifs: 2han_A kGAACc
2han_AB GGTTCAnTncaC
4umm_AE GTtCAntnnAC
Publications: Jakób M, Kołodziejczyk R, Orłowski M, Krzywda S, Kowalska A, Dutko-Gwóźdź J, Gwóźdź T, Kochman M, Jaskólski M, Ozyhar A. Novel DNA-binding element within the C-terminal extension of the nuclear receptor DNA-binding domain. Nucleic acids research 35:2705-18 (2007). [Pubmed]

Maletta M, Orlov I, Roblin P, Beck Y, Moras D, Billas I.M, Klaholz B.P. The palindromic DNA-bound USP/EcR nuclear receptor adopts an asymmetric organization with allosteric domain positioning. Nature communications 5:4139 (2014). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.