DNA Binding Site

Accessions: TAATAATA (UniPROBE 20160601), MA1824.2.18 (JASPAR 2024)
Organisms: Mus musculus, Saccharomyces cerevisiae, Zea mays
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: TAATAATA
Type: Heterodimer
Binding TFs: UP00325A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
UP00255A (Homeobox domain)
C0PNY4 (Homeobox domain, Homeobox associated leucine zipper)
C0PNY4
Binding Motifs: UP00255A_1 twrttaATTAwtaawwr
UP00325A_1 yttwyywwTATAwwwwrkdv
MA1824.2 cAATAATt
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

Sessa G., Morelli G., Ruberti I. The Athb-1 and -2 HD-Zip domains homodimerize forming complexes of different DNA binding specificities. EMBO J. 12:3507-3517 (1993). [Pubmed]

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