DNA Binding Site

						

			
Accessions: AAAGGTCA (UniPROBE 20160601), MA1112.3.13 (JASPAR 2024), MA1112.3.14 (JASPAR 2024), MA1112.3.15 (JASPAR 2024), MA1112.3.16 (JASPAR 2024)

			
Organisms: Mus musculus, Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: AAAGGTCA
Type: Heterodimer
Binding TFs: UP00066A (Zinc finger, C4 type (two domains))
UP00079A (Zinc finger, C4 type (two domains))
P22736 (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
UP00606A (Zinc finger, C4 type (two domains))
UP00607A (Zinc finger, C4 type (two domains))
UP00607E (Zinc finger, C4 type (two domains))
P22736
Binding Motifs: UP00066A_1 skymmGGGGTCAAytkm
UP00079A_1 kmkyCAAGGTCAtrykm
UP00066A_2 kkchAAAGTCCAmthw
UP00079A_2 vkbkAGGGGTCAarssm
UP00606A_1 mywgvhhTmGAGGTCAwmbwrsy
UP00607A_1 kmwdwycAAAGATCAagmktad
UP00607E_1 kmwktycAAAGATCAmgaktad
MA1112.3 AAAGGTCA
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]


Wansa KD, Harris JM, Muscat GE. The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment. J Biol Chem 277:33001-11 (2002). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.