DNA Binding Motif

Accessions: UP00066A_2 (UniPROBE 20160601)
Names: alpha, D19Mgi10, hepatic nuclear factor 4, Hepatocyte nuclear factor 4-alpha, Hnf-4, HNF-4-alpha, HNF4 alpha, Hnf4a, MODY1, Nr2a1, Nuclear receptor 2A1, Tcf14, Tcf4, Transcription factor 14, Transcription factor HNF-4
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: kkchAAAGTCCAmthw
Weblogo:
PSSM: P0 A C G T
01 0.13 0.17 0.35 0.35 k
02 0.11 0.14 0.37 0.37 k
03 0.20 0.41 0.16 0.23 c
04 0.31 0.31 0.12 0.26 h
05 0.90 0.01 0.04 0.05 A
06 0.78 0.02 0.17 0.03 A
07 0.95 0 0.04 0 A
08 0 0 0.99 0.01 G
09 0 0 0.01 0.98 T
10 0.02 0.97 0 0.01 C
11 0 0.98 0 0.01 C
12 0.89 0 0.10 0.01 A
13 0.51 0.31 0.07 0.11 m
14 0.18 0.12 0.13 0.57 t
15 0.29 0.28 0.17 0.27 h
16 0.32 0.23 0.13 0.32 w
Binding TFs: UP00066A (Zinc finger, C4 type (two domains))
Binding Sites: AAAGGTCA
AAAGTCCA
AAGTCCAA
AGAGTCCA
AGGGGTCA
AGGGTCAA
AGGGTCCA
ATGACCCC
ATGGACCC
CGGGGTCA
CGGGTCCA
CTGACCCC
GAGTCCAA
GGGGTCAA
GGGTCAAA
GGGTCAAC
GGGTCCAA
GGGTCCAC
TGACCCCA
TGGACCCA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.