DNA Binding Motif

Accessions: MA0482.3 (JASPAR 2024)
Names: GATA4
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 8
Consensus: cCTTATCT
Weblogo:
PSSM: P0 A C G T
01 3977 38289 5099 11649 c
02 3150 50062 1103 4699 C
03 1586 1429 749 55250 T
04 1650 1377 808 55179 T
05 54420 1703 1245 1646 A
06 770 582 539 57123 T
07 480 56544 568 1422 C
08 7659 1792 1376 48187 T
Type: Heterodimer
Binding TFs: P43694 (GATA zinc finger, GATA-type transcription activator, N-terminal )
P43694
Binding Sites: MA0482.3.11 / MA0482.3.16 / MA0482.3.18 / MA0482.3.2
MA0482.3.20 / MA0482.3.3
MA0482.3.14 / MA0482.3.4 / MA0482.3.5
MA0482.3.1 / MA0482.3.17 / MA0482.3.19 / MA0482.3.8
MA0482.3.10 / MA0482.3.12 / MA0482.3.15 / MA0482.3.7
MA0482.3.13
MA0482.3.6
MA0482.3.9
Publications: Yamagata T, Nishida J, Sakai R, Tanaka T, Honda H, Hirano N, Mano H, Yazaki Y, Hirai H. Of the GATA-binding proteins, only GATA-4 selectively regulates the human interleukin-5 gene promoter in interleukin-5-producing cells which express multiple GATA-binding proteins. Molecular and cellular biology 15:3830-9 (1995). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.