DNA Binding Site
| Accessions: | MA0037.5.20 (JASPAR 2024), MA0037.5.3 (JASPAR 2024), MA0482.3.14 (JASPAR 2024), MA0482.3.4 (JASPAR 2024), MA0482.3.5 (JASPAR 2024), MA1104.3.11 (JASPAR 2024), MA1104.3.4 (JASPAR 2024), MA1104.3.8 (JASPAR 2024), MA1701.2.10 (JASPAR 2024), MA1701.2.6 (JASPAR 2024), MA1970.2.10 (JASPAR 2024), MA1970.2.11 (JASPAR 2024), MA2106.1.17 (JASPAR 2024), MA2165.1.18 (JASPAR 2024) |
| Organisms: | Mus musculus, Homo sapiens, Caenorhabditis elegans, Zea mays |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | TCTTATCT |
| Type: | Heterodimer |
| Binding TFs: | P23772 (GATA zinc finger) Q92908 (GATA zinc finger, GATA-type transcription activator, N-terminal ) P43694 (GATA zinc finger, GATA-type transcription activator, N-terminal ) Q10655 (GATA zinc finger) B4FLJ6 (Myb-like DNA-binding domain) Q9UHF7 (GATA zinc finger) B4FLJ6 P23772 P28515 P43694 Q10655 Q92908 Q9UHF7 |
| Binding Motifs: | MA0037.5 tCTTATCT MA0482.3 cCTTATCT MA1104.3 TCTTATCT MA1701.2 tCTTATCA MA1970.2 TCTTATCT MA2106.1 cCTTATCC MA2165.1 TCTTATCT |
| Publications: | Merika M., Orkin S. H. DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13:3999-4010 (1993). [Pubmed] Yamagata T, Nishida J, Sakai R, Tanaka T, Honda H, Hirano N, Mano H, Yazaki Y, Hirai H. Of the GATA-binding proteins, only GATA-4 selectively regulates the human interleukin-5 gene promoter in interleukin-5-producing cells which express multiple GATA-binding proteins. Molecular and cellular biology 15:3830-9 (1995). [Pubmed] Shaw-White J. R., Bruno M. D., Whitsett J. A. GATA-6 activates transcription of thyroid transcription factor-1.. J. Biol. Chem. 274:2658-2664 (1999). [Pubmed] Hawkins MG, McGhee JD. elt-2, a second GATA factor from the nematode Caenorhabditis elegans. J Biol Chem 270:14666-71 (1995). [Pubmed] Serandour AA, Mohammed H, Miremadi A, Mulder KW, Carroll JS. TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers. Oncogene 37:5281-5291 (2018). [Pubmed] Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] Shim YH. elt-1, a gene encoding a Caenorhabditis elegans GATA transcription factor, is highly expressed in the germ lines with msp genes as the potential targets. Mol Cells 9:535-41 (1999). [Pubmed] |
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