DNA Binding Site

Accessions: MA0037.5.15 (JASPAR 2024), MA0037.5.2 (JASPAR 2024), MA0037.5.6 (JASPAR 2024), MA0037.5.7 (JASPAR 2024), MA0482.3.20 (JASPAR 2024), MA0482.3.3 (JASPAR 2024), MA1104.3.18 (JASPAR 2024), MA1104.3.2 (JASPAR 2024), MA1104.3.20 (JASPAR 2024), MA1701.2.9 (JASPAR 2024), MA1970.2.7 (JASPAR 2024)
Organisms: Mus musculus, Homo sapiens, Caenorhabditis elegans
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: CCTTATCT
Type: Heterodimer
Binding TFs: P23772 (GATA zinc finger)
Q92908 (GATA zinc finger, GATA-type transcription activator, N-terminal )
P43694 (GATA zinc finger, GATA-type transcription activator, N-terminal )
Q10655 (GATA zinc finger)
Q9UHF7 (GATA zinc finger)
P23772
P43694
Q10655
Q92908
Q9UHF7
Binding Motifs: MA0037.5 tCTTATCT
MA0482.3 cCTTATCT
MA1104.3 TCTTATCT
MA1701.2 tCTTATCA
MA1970.2 TCTTATCT
Publications: Merika M., Orkin S. H. DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13:3999-4010 (1993). [Pubmed]

Yamagata T, Nishida J, Sakai R, Tanaka T, Honda H, Hirano N, Mano H, Yazaki Y, Hirai H. Of the GATA-binding proteins, only GATA-4 selectively regulates the human interleukin-5 gene promoter in interleukin-5-producing cells which express multiple GATA-binding proteins. Molecular and cellular biology 15:3830-9 (1995). [Pubmed]

Shaw-White J. R., Bruno M. D., Whitsett J. A. GATA-6 activates transcription of thyroid transcription factor-1.. J. Biol. Chem. 274:2658-2664 (1999). [Pubmed]

Hawkins MG, McGhee JD. elt-2, a second GATA factor from the nematode Caenorhabditis elegans. J Biol Chem 270:14666-71 (1995). [Pubmed]

Serandour AA, Mohammed H, Miremadi A, Mulder KW, Carroll JS. TRPS1 regulates oestrogen receptor binding and histone acetylation at enhancers. Oncogene 37:5281-5291 (2018). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.