DNA Binding Motif

						

			
Accessions: UP00511A_1 (UniPROBE 20160601)

			
Names: CG7895, Dmel\CG7895, DmNK-4, DROHOXHK4, DROHOXNK4, msh-2, msh2, Muscle-specific homeobox protein tinman, NK-4/msh-2, NK4/msh-2, Tin, tin/NK4, Tinman
Organisms: Drosophila melanogaster
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 23
Consensus: aagrcwtawCCACTTAwrwwymA
Weblogo: 
PSSM: P0      A      C      G      T
01   0.39   0.14   0.22   0.24      a
02   0.63   0.21   0.08   0.08      a
03   0.21   0.12   0.63   0.04      g
04   0.30   0.14   0.38   0.17      r
05   0.20   0.39   0.20   0.21      c
06   0.31   0.24   0.11   0.34      w
07   0.24   0.11   0.12   0.53      t
08   0.66   0.05   0.18   0.11      a
09   0.46   0.05   0.21   0.28      w
10   0.04   0.89   0.05   0.01      C
11   0.01   0.92      0   0.07      C
12   0.95      0      0   0.05      A
13   0.04   0.95      0      0      C
14   0.01   0.01      0   0.98      T
15      0   0.03      0   0.96      T
16   0.85   0.02   0.12   0.01      A
17   0.50   0.04   0.07   0.40      w
18   0.49   0.15   0.28   0.08      r
19   0.30   0.17   0.20   0.32      w
20   0.38   0.16   0.20   0.25      w
21   0.22   0.25   0.17   0.36      y
22   0.26   0.42   0.11   0.21      m
23   0.69   0.06   0.06   0.19      A
Binding TFs: UP00511A (Homeobox domain)
Binding Sites: ACACTTGA
ACCACTTA
ATAAGTGG
CACTTAAA
CACTTAAG
CACTTGAA
CACTTGAG
CCACTTAA
CCACTTAG
CCACTTGA
CTCAAGTA
GCACTTAA
GCACTTGA
GCCACTTA
GGTACTTA
GTACTTAA
GTACTTGA
TAAGTGGA
ACAAGTGG
ATACTTGA
			
Publications: Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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