DNA Binding Motif

						

			
Accessions: 1apl_CD (3D-footprint 20231221)

			
Names: PROTEIN (MAT-ALPHA2 HOMEODOMAIN)
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF A MAT-ALPHA2 HOMEODOMAIN-OPERATOR COMPLEX SUGGESTS A GENERAL MODEL FOR HOMEODOMAIN-DNA INTERACTIONS
Length: 16
Consensus: TTGTAnTTnATnTACA
Weblogo: 
PSSM: P0      A      C      G      T
01      3      3      3     87      T
02      0      0      0     96      T
03      0      0     96      0      G
04      0      0      0     96      T
05     69     12      6      9      A
06     24     24     24     24      n
07      3      3      3     87      T
08      3      3      3     87      T
09     24     24     24     24      n
10     78      3     12      3      A
11     12      3      6     75      T
12     24     24     24     24      n
13      3      3      3     87      T
14     96      0      0      0      A
15      0     96      0      0      C
16     87      3      3      3      A
Type: Heterodimer
Binding TFs: 1apl_C (Homeobox domain, Homeobox KN domain)
1apl_D (Homeobox domain, Homeobox KN domain)
Binding Sites: 1apl_A
1apl_B
			
Publications: Wolberger C., Vershon A. K., Liu B., Johnson A. D., Pabo C. O. Crystal structure of a MATalpha2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions. Cell 67:517-528 (1991). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.