DNA Binding Motif

						

			
Accessions: TFAP4_MAX_1 (HumanTF2 1.0)

			
Names: TFAP4_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: yCAGCTGrmvrsCACGTGs
Weblogo: 
PSSM: P0      A      C      G      T
01   2360   2449   1831   3094      y
02     23   9734      2    224      C
03   9734    138    158    293      A
04     63   2304   9734   1272      G
05   1073   9734   2474     47      C
06    130    896    299   9734      T
07     55    121   9734     67      G
08   2714   2353   2657   2010      r
09   2743   2973   2129   1889      m
10   2521   2784   2447   1983      v
11   2895   2105   3506   1228      r
12   1604   2989   3617   1525      s
13    221   9734    101     37      C
14   9734     73    310    154      A
15     70   9734    266    721      C
16    693    503   9734    103      G
17     81    201    115   9734      T
18     91     95   9734    123      G
19   1099   4027   2606   2002      s
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
TFAP4_TF1 (Helix-loop-helix DNA-binding domain)
TFAP4_Full (Helix-loop-helix DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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