DNA Binding Motif

						

			
Accessions: MEIS1_DLX3 (HumanTF2 1.0)

			
Names: MEIS1_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: TGACAgsyTAATtr
Weblogo: 
PSSM: P0      A      C      G      T
01    483    664    418   7449      T
02     17     19   7449      0      G
03   7449     33    226    464      A
04      0   7449     22      0      C
05   7449     64    691    104      A
06    897   1546   4013    993      g
07    787   3366   4083    781      s
08   1423   2219    544   3264      y
09   1409    612    129   7449      T
10   7449    182    544      0      A
11   7449      5     54    125      A
12    380    171   1534   7449      T
13   2107   1522   1607   7449      t
14   3003    607   7449    840      r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
MEIS1_TF1 (Homeobox domain, Homeobox KN domain)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
MEIS1_Crystal (Homeobox domain, Homeobox KN domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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