DNA Binding Motif

Accessions: UP00401A_1 (UniPROBE 20160601)
Names: ecotropic viral integration site 16, EVI16, OTTHUMP00000039358, Sox4, SRY (sex determining region Y)-box 4, SRY-related HMG-box gene 4, Transcription factor SOX-4
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 14
Consensus: tadAACAAwGrvrw
Weblogo:
PSSM: P0 A C G T
01 0.25 0.20 0.23 0.33 t
02 0.37 0.17 0.24 0.23 a
03 0.31 0.11 0.29 0.29 d
04 0.76 0.03 0.16 0.05 A
05 0.95 0 0 0.04 A
06 0 0.94 0.02 0.04 C
07 0.98 0 0.01 0.01 A
08 0.98 0.01 0 0 A
09 0.62 0.01 0.01 0.37 w
10 0.14 0.01 0.84 0.01 G
11 0.30 0.14 0.55 0.01 r
12 0.27 0.33 0.32 0.08 v
13 0.30 0.23 0.29 0.18 r
14 0.28 0.23 0.16 0.33 w
Binding TFs: UP00401A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: AAACAAAG
AAACAATA
AAACAATG
AACAAAGA
AACAAAGG
AACAATAG
AACAATGA
AACAATGG
ACAAAGAA
ACAAAGAG
ACAAAGGA
ACAAAGGG
AGACAAAG
AGACAATG
ATTGTTCC
ATTGTTTG
CAACAATA
CATTGTTC
CTTTGTTA
CTTTGTTC
Publications: Scharer CD, McCabe CD, Ali-Seyed M, Berger MF, Bulyk ML, Moreno CS. Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer. Cancer Research. January 15, 2009. 69(2). [Pubmed]

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