Transcription Factor
Accessions: | 5ed4_A (3D-footprint 20231221) |
Names: | P71814_MYCTU, Response regulator |
Organisms: | Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | A0A045 |
Length: | 222 |
Pfam Domains: | 6-115 Response regulator receiver domain 144-218 Transcriptional regulatory protein, C terminal |
Sequence: (in bold interface residues) | 1 TPEARVLVVDDEANIVELLSVSLKFQGFEVYTATNGAQALDRARETRPDAVILDVMMPGM 60 61 DGFGVLRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILR 120 121 RAGVRLTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILDHVWRY 180 181 DFGGDVNVVESYVSYLRRKIDTGEKRLLHTLRGVGYVLREPR |
Interface Residues: | 186, 187, 188, 190, 191, 192, 194, 195, 212 |
3D-footprint Homologues: | 8jo2_H, 8hih_Q, 5ed4_A, 8hml_B, 2z33_A, 5x5l_H, 4kfc_B, 7e1b_B, 4nhj_A |
Binding Motifs: | 5ed4_A AGCTGTGA 5ed4_AB ynCAGcwnnnTCnCAG |
Binding Sites: | 5ed4_C 5ed4_D |
Publications: | He X, Wang L, Wang S. Structural basis of DNA sequence recognition by the response regulator PhoP in Mycobacterium tuberculosis. Sci Rep : (2016). [Pubmed] |
Related annotations: | PaperBLAST |
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