Transcription Factor

						

			
Accessions: 5ed4_A (3D-footprint 20231221)

			
Names: P71814_MYCTU, Response regulator
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: A0A045
Length: 222
Pfam Domains:     6-115 Response regulator receiver domain
  144-218 Transcriptional regulatory protein, C terminal
Sequence: 
(in bold interface residues)		   1 TPEARVLVVDDEANIVELLSVSLKFQGFEVYTATNGAQALDRARETRPDAVILDVMMPGM   60
  61 DGFGVLRRLRADGIDAPALFLTARDSLQDKIAGLTLGGDDYVTKPFSLEEVVARLRVILR  120
 121 RAGVRLTFADIELDEETHEVWKAGQPVSLSPTEFTLLRYFVINAGTVLSKPKILDHVWRY  180
 181 DFGGDVNVVESYVSYLRRKIDTGEKRLLHTLRGVGYVLREPR
Interface Residues: 186, 187, 188, 190, 191, 192, 194, 195, 212
3D-footprint Homologues: 8jo2_H, 5ed4_A, 8hml_B, 2z33_A, 5x5l_H, 4kfc_B, 7e1b_B, 4nhj_A, 8hih_Q
Binding Motifs: 5ed4_A AGCTGTGA
5ed4_AB ynCAGcwnnnTCnCAG
Binding Sites: 5ed4_C
5ed4_D
			
Publications: He X, Wang L, Wang S. Structural basis of DNA sequence recognition by the response regulator PhoP in Mycobacterium tuberculosis. Sci Rep : (2016). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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