DNA Binding Site

Accessions: 5ed4_C (3D-footprint 20231221), 5ed4_G (3D-footprint 20231221)
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 25
Sequence: ATTCACAGCTGATTCACAGCATCTA
Type: Heterodimer
Binding TFs: 5ed4_A (Response regulator receiver domain, Transcriptional regulatory protein, C terminal)
5ed4_B (Response regulator receiver domain, Transcriptional regulatory protein, C terminal)
5ed4_F (Response regulator receiver domain, Transcriptional regulatory protein, C terminal)
Binding Motifs: 5ed4_A AGCTGTGA
5ed4_AB ynCAGcwnnnTCnCAG
5ed4_EF tCnCAGnnnnnTCaCAG
Publications: He X, Wang L, Wang S. Structural basis of DNA sequence recognition by the response regulator PhoP in Mycobacterium tuberculosis. Sci Rep : (2016). [Pubmed]

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