Transcription Factor

Accessions: 1jt0_A (3D-footprint 20231221), 1jt0_B (3D-footprint 20231221), 1jt0_C (3D-footprint 20231221)
Names: HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, QACR_STAAU
Organisms: Staphylococcus aureus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0A0N4
Length: 188
Pfam Domains: 6-52 Bacterial regulatory proteins, tetR family
56-187 QacR-like protein, C-terminal region
Sequence:
(in bold interface residues)
1 NLKDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFKTKENLFLEILNIEESKW 60
61 QEQWKKEQIKAKTNREKFYLYNELSLTTEYYYPLQNAIIEFYTEYYKTNSINEKMNKLEN 120
121 KYIDAYHVIFKEGNLNGEWSINDVNAVSKIAANAVNGIVTFTHEQNINERIKLMNKFSQI 180
181 FLNGLSKH
Interface Residues: 23, 24, 25, 34, 35, 36, 37, 39, 40, 43, 44
3D-footprint Homologues: 7xaq_B, 5yej_B, 6nsn_B, 1jt0_C, 5fmp_B, 5gpc_B, 6gy3_A, 4l62_M, 6c31_A, 1qpi_A, 4pxi_B, 7amn_A, 6o6p_B, 7jnp_A, 6en8_C, 6wpa_A, 6yl2_A
Binding Motifs: 1jt0_ABCD ATngACCnATCGAnnGGTcTAT
1jt0_C ATAGACC
Binding Sites: 1jt0_E / 1jt0_F
Publications: Schumacher M.A, Miller M.C, Grkovic S, Brown M.H, Skurray R.A, Brennan R.G. Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR. The EMBO journal 21:1210-8 (2002). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.