DNA Binding Motif
Accessions: | 1jt0_ABCD (3D-footprint 20231221) |
Names: | HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION |
Organisms: | Staphylococcus aureus |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Description: | Crystal structure of a cooperative QacR-DNA complex |
Length: | 22 |
Consensus: | ATngACCnATCGAnnGGTcTAT |
Weblogo: | |
PSSM: | P0 A C G T 01 92 3 0 1 A 02 0 1 1 94 T 03 24 24 24 24 n 04 15 11 59 11 g 05 96 0 0 0 A 06 0 96 0 0 C 07 0 96 0 0 C 08 24 24 24 24 n 09 82 1 3 10 A 10 0 0 0 96 T 11 0 96 0 0 C 12 0 0 96 0 G 13 96 0 0 0 A 14 24 24 24 24 n 15 24 24 24 24 n 16 0 0 96 0 G 17 0 0 96 0 G 18 0 0 0 96 T 19 19 46 17 14 c 20 9 13 7 67 T 21 96 0 0 0 A 22 1 1 4 90 T |
Type: | Heterodimer |
Binding TFs: | 1jt0_A / 1jt0_B / 1jt0_C (Bacterial regulatory proteins, tetR family, QacR-like protein, C-terminal region) 1jt0_D (Bacterial regulatory proteins, tetR family, QacR-like protein, C-terminal region) |
Binding Sites: | 1jt0_E / 1jt0_F |
Publications: | Schumacher M.A, Miller M.C, Grkovic S, Brown M.H, Skurray R.A, Brennan R.G. Structural basis for cooperative DNA binding by two dimers of the multidrug-binding protein QacR. The EMBO journal 21:1210-8 (2002). [Pubmed] |
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