Transcription Factor
Accessions: | UP00048A (UniPROBE 20160601) |
Names: | alpha, Nr1b1, RAR alpha 1, RAR-alpha, Rara, RARalpha1, retinoic acid receptor, Retinoic acid receptor alpha |
Organisms: | Mus musculus |
Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
Uniprot: | P11416 |
Description: | retinoic acid receptor, alpha |
Length: | 107 |
Pfam Domains: | 18-86 Zinc finger, C4 type (two domains) |
Sequence: (in bold interface residues) | 1 EIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKN 60 61 CIINKVTRNRCQYCRLQKCFDVGMSKESVRNDRNKKKKEAPKPECSE |
Interface Residues: | 27, 28, 30, 31, 37, 38, 39, 40, 41, 43, 44, 45, 48, 50, 54, 69, 73, 75, 77, 91, 93, 95, 98 |
3D-footprint Homologues: | 6fbq_A, 6l6q_B, 7wnh_D, 1lo1_A, 3g9m_B, 1a6y_A, 4oln_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 7xv6_B, 4iqr_B, 2han_A, 1hcq_E, 8cef_H, 2han_B, 1kb2_B, 2a66_A, 8hbm_B, 5krb_G, 2nll_B, 1lat_A, 4yhx_A, 4hn5_B, 5e69_A, 3g6t_A, 1r4i_A, 5emc_A, 7prw_B, 5cbx_B, 4tnt_B, 5cbz_E |
Binding Motifs: | UP00048A_1 kmycAAAGGTCAcstg UP00048A_2 akagysGGGTCAakkm |
Binding Sites: | AAGGTCAA AAGGTCAC AAGGTCAT AATGACCT AGAGGTCA AGGGGTCA AGGTCAAA AGGTCAAG AGGTCACA AGGTCACC AGGTCACG AGGTCAGC AGGTCATC CAAGGTCA CGAGGTCA GAAGGTCA GAGGTCAA GAGGTCAC TAAGGTCA CTGACCTC |
Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.