Transcription Factor
| Accessions: | UP00303A (UniPROBE 20160601) |
| Names: | Fhl1, P8283.15, Pre-rRNA-processing protein FHL1, YPR104C |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P39521 |
| Description: | Putative transcriptional regulator with similarity to DNA-binding domain of Drosophila forkhead; required for rRNA processing |
| Length: | 207 |
| Pfam Domains: | 51-139 Fork head domain |
| Sequence: (in bold interface residues) | 1 KNEPKSKKKITTGAKPKKAQTKPAVKKEKKPPKIPKKVYTLEEIPVEYRTKPTVSYSAML 60 61 TTCIRKYSTAKGMSLSEIYAGIRELFPYYKYCPDGWQSSVRHNLSLNKSFRKVSKEGKGW 120 121 LWGLDEEYIAERERQKKKQSEIAVAKAQAAQLKLEQQQHKLQQVPQRGKKDIVSQRSNVN 180 181 ARKQNISQTLAANRAASNRKNTASDNQ |
| Interface Residues: | 95, 97, 98, 99, 101, 102, 103, 105, 106, 115, 118 |
| 3D-footprint Homologues: | 7vox_H, 2hdc_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 3qrf_G |
| Binding Motifs: | UP00303A_1 rrwawtGACGCAawtwhgwk |
| Binding Sites: | TGACGCAA ACGCAAAC ACGCAAAT ACGCAATA AGACGCAA AGTGCGTC ATTGCGTC CGACGCAA CGTGCGTC GACGCAAA GACGCAAC GACGCACA GACGCATA GCGACGCA GTGACGCA GTGCGTCA TGCGTCAA ACACGCAA CGACGCAC GGGACGCA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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