Transcription Factor

Accessions: UP00093A (UniPROBE 20160601)
Names: Klf7, Krueppel-like factor 7, Kruppel-like factor 7 (ubiquitous)
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q99JB0
Description: Kruppel-like factor 7 (ubiquitous): Mus musculus Kruppel-like factor 7 (ubiquitous) (Klf7), mRNA
Length: 99
Pfam Domains: 16-40 C2H2-type zinc finger
16-40 Zinc finger, C2H2 type
32-53 Zinc-finger double domain
46-70 C2H2-type zinc finger
46-70 Zinc finger, C2H2 type
63-86 Zinc-finger double domain
76-98 C2H2-type zinc finger
76-98 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 GGGGADTCPENKKRVHRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARS 60
61 DELTRHYRKHTGAKPFKCNHCDRCFSRSDHLALHMKRHI
Interface Residues: 28, 29, 30, 31, 32, 34, 35, 37, 38, 41, 57, 58, 59, 60, 61, 62, 64, 65, 66, 69, 86, 87, 88, 89, 90, 91, 92, 93, 94, 97
3D-footprint Homologues: 6ml4_A, 5v3j_F, 7n5w_A, 3uk3_C, 1tf3_A, 6jnm_A, 1g2f_F, 7eyi_G, 1tf6_A, 2i13_A, 6blw_A, 5kkq_D, 1ubd_C, 6u9q_A, 5ei9_F, 1mey_C, 5kl3_A, 7ysf_A, 6wmi_A, 2kmk_A, 5und_A, 2gli_A, 8h9h_G, 2lt7_A, 7y3m_I, 6e94_A, 6a57_A, 2jpa_A, 5k5i_A, 7w1m_H, 7y3l_A, 4m9v_C, 8cuc_F, 4x9j_A, 8gn3_A, 1llm_D, 2wbs_A, 5yel_A, 7txc_E, 2drp_D, 1f2i_J, 8ssq_A, 5k5l_F, 5yj3_D
Binding Motifs: UP00093A_1 tyrrCCmCGCCChyww
UP00093A_2 varywTACGCCChamwk
Binding Sites: CCCGCCCC
AACGCCCA
AAGGGCGT
ACGCCCAC
ACGCCCAT
ACGCCCCC
ACGCCCCT
ACGCCCTA
AGGGCGGA
AGGGCGGG
AGGGCGTG
CACGCCCA
CACGCCCC
CCACACCC
CCACGCCC
CCCCACCC
CCCGCCCA
CTACGCCC
GGGGCGTA
ACACGCCC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.