Transcription Factor

Accessions: UP00458A (UniPROBE 20160601)
Names: CYP1, Hap1, Heme Activator Protein
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: Heme Activator Protein : Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus
Length: 39
Sequence:
(in bold interface residues)
1 LDPTDINYSTNMAGVVDQIHDYTTSNRNSLTPQYSIAAG
Interface Residues: 13
3D-footprint Homologues: 2pyl_A
Binding Motifs: UP00458A_1 / UP00458A_2 scrwycyCGGAGwTAAcgccsky
UP00458A_3 TCGGCCGA
Binding Sites: AACTCCGA
AACTCCGG
AATCTCCG
ATCTCCGA
ATCTCCGG
CGGAAATA
CGGAATTA
CGGACATA
CGGACTTA
CGGAGATA
CGGAGTTA
CGGATATA
CGGATTTA
CGGGGATA
CGGGTTTA
TCGGCCGA
AAATCCGG
CGGCGATA
CGGCGTTA
CGGGGTTA
Publications: Gordân R, Murphy KF, McCord RP, Zhu C, Vedenko A, Bulyk ML. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol : (2011). [Pubmed]
Related annotations: PaperBLAST

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