Transcription Factor
| Accessions: | UP00053A (UniPROBE 20160601) |
| Names: | 9530071D11Rik, Nr2b1, Retinoic acid receptor RXR-alpha, retinoid X receptor alpha, RXR alpha 1, Rxra, RXRalpha1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P28700 |
| Description: | retinoid X receptor alpha: retinoid X receptor alpha (Rxra), mRNA |
| Length: | 107 |
| Pfam Domains: | 18-86 Zinc finger, C4 type (two domains) |
| Sequence: (in bold interface residues) | 1 LKVPAHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKD 60 61 CLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVEST |
| Interface Residues: | 27, 28, 30, 31, 37, 38, 40, 41, 44, 45, 69, 91, 93, 95, 98 |
| 3D-footprint Homologues: | 6fbq_A, 6l6q_B, 7wnh_D, 1a6y_A, 1lo1_A, 3g9m_B, 4oln_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E |
| Binding Motifs: | UP00053A_1 tshykTGACCCCdyrmt UP00053A_2 kcrcrwAGktyrtwmk |
| Binding Sites: | AAGGTCAC AAGGTCAT AATGACCT AGAGGTCA AGGGGTCA AGGGTCAA AGGTCAAG AGGTCACC AGGTCATC ATGACCCC CAAGGTCA CGAGGTCA CGGGGTCA CTGACCCC GAGGTCAA GAGGTCAC GATGACCC GGGGTCAA GGGGTCAC TGACCCCA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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