Transcription Factor

						

			
Accessions: UP00042A (UniPROBE 20160601)

			
Names: (NCBI), gene model 397, Gm397, LOC245109
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Q3URS2
Description: gene model 397, (NCBI): Mus musculus similar to Zinc finger protein 58 (Zfp-58) (Zinc finger protein Mfg-1) (LOC212386), mRNA
Length: 127
Pfam Domains:     16-38 Zinc finger, C2H2 type
    16-38 C2H2-type zinc finger
    30-56 Zinc-finger double domain
    47-66 C2H2-type zinc finger
    61-84 Zinc-finger double domain
    73-95 Zinc finger, C2H2 type
    73-93 C2H2-type zinc finger
    73-92 Zinc-finger of C2H2 type
   87-111 Zinc-finger double domain
  101-124 Zinc finger, C2H2 type
  101-124 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 PCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDR   60
  61 RTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHL  120
 121 RNYHRSD
Interface Residues: 26, 27, 28, 29, 30, 32, 33, 35, 36, 37, 39, 55, 56, 57, 58, 59, 61, 62, 65, 83, 84, 85, 86, 87, 90, 98, 111, 112, 113, 114, 115, 117, 118, 122
3D-footprint Homologues: 7w1m_H, 8ssq_A, 2drp_D, 8ssu_A, 2gli_A, 5v3j_F, 7ysf_A, 6e94_A, 2jpa_A, 1ubd_C, 1tf3_A, 8cuc_F, 7y3l_A, 7n5w_A, 2kmk_A, 6u9q_A, 1tf6_A, 8h9h_G, 2lt7_A, 8gn3_A, 7txc_E, 7y3m_I, 1yuj_A
Binding Motifs: UP00042A_1 mwdaTGTGCACAymmky
UP00042A_2 rrmrGCACACACkcmm
Binding Sites: ACTGCACA
AGTGCACA
AGTGTGCA
ATGTGCAC
CGTGCACA
CTGCACAC
CTGTGCAC
GATGTGCA
GCACACAA
GCACATAA
GCTGTGCA
GGTGCACA
GGTGTGCA
GTGCACAA
GTGCACAC
TATGTGCA
TCTGTGCA
TGCACACA
TGTGCACA
AATGCACA
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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