DNA Binding Site

Accessions: 1zq3_A (3D-footprint 20231221), 2lkx_B (3D-footprint 20231221)
Organisms: Drosophila melanogaster, Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 13
Sequence: GCTCTAATCCCCG
Type: Heterodimer
Binding TFs: 1zq3_P (Homeobox domain, Homeodomain leucine-zipper encoding, Homez)
2lkx_A (Homeobox domain)
Binding Motifs: 1zq3_P gGGAtTAG
2lkx_A GgATTAG
Publications: Baird-Titus J.M, Clark-Baldwin K, Dave V, Caperelli C.A, Ma J, Rance M. The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site. Journal of molecular biology 356:1137-51 (2006). [Pubmed]

Chaney B.A, Clark-Baldwin K, Dave V, Ma J, Rance M. Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome. Biochemistry 44:7497-511 (2005). [Pubmed]

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