Transcription Factor

Accessions: 1zq3_P (3D-footprint 20231221)
Names: BCD_DROME, Homeotic bicoid protein, Homeotic protein bicoid, PRD-4
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P09081
Length: 68
Pfam Domains: 3-58 Homeobox domain
12-56 Homeodomain leucine-zipper encoding, Homez
Sequence:
(in bold interface residues)
1 GPRRTRTTFTSSQIAELEQHFLQGRYLTAPRLADLSAKLALGTAQVKIWFKNRRRRHKIQ 60
61 SDQHKDQS
Interface Residues: 3, 4, 5, 6, 44, 45, 47, 48, 51, 52, 55, 56, 59
3D-footprint Homologues: 1fjl_B, 1puf_A, 1ig7_A, 6a8r_A, 2h1k_B, 3cmy_A, 5zfz_A, 6fqp_B, 3d1n_M, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 2ld5_A, 7q3o_C, 5zjt_E, 4cyc_A, 1b72_A, 5hod_A, 3l1p_A, 3a01_E, 5jlw_D, 1puf_B, 6es3_K, 4xrs_G, 2hdd_A, 7psx_B, 3rkq_B, 2r5y_A, 1au7_A, 5flv_I, 2hos_A, 2xsd_C, 1le8_A, 7xrc_C, 1e3o_C, 1o4x_A, 6fqq_E, 4qtr_D, 1mnm_C, 1du0_A, 8g87_X, 1xpx_A, 1k61_B
Binding Motifs: 1zq3_P gGGAtTAG
Binding Sites: 1zq3_A
1zq3_B
Publications: Baird-Titus J.M, Clark-Baldwin K, Dave V, Caperelli C.A, Ma J, Rance M. The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site. Journal of molecular biology 356:1137-51 (2006). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.