DNA Binding Site

Accessions: PF0007.1.4 (JASPAR 2024), PF0007.1.5 (JASPAR 2024), MA0462.3.20 (JASPAR 2024), MA0835.3.10 (JASPAR 2024), MA0835.3.17 (JASPAR 2024), MA1634.2.14 (JASPAR 2024), MA1928.2.5 (JASPAR 2024), UN0799.1.1 (JASPAR 2024)
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 7
Sequence: TGAATCA
Type: Heterodimer
Binding TFs: Q16520 (bZIP transcription factor, Basic region leucine zipper)
Q9NR55 (bZIP transcription factor, Basic region leucine zipper)
Q6ZN30 (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, C2H2-type zinc finger)
Q16520
Q6ZN30
Q9NR55
Q9Y2D1
Binding Motifs: PF0007.1 TGAsTCA
MA0462.3 TGACTCA
MA0835.3 TGACTCA
MA1634.2 TGACTCA
MA1928.2 TGAGTCA
UN0799.1 TGAGTCA
Publications: Xie X, Lu J, Kulbokas E.J, Golub T.R, Mootha V, Lindblad-Toh K, Lander E.S, Kellis M. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434:338-45 (2005). [Pubmed]

Li P, Spolski R, Liao W, Wang L, Murphy TL, Murphy KM, Leonard WJ. BATF-JUN is critical for IRF4-mediated transcription in T cells. Nature 490:543-6 (2012). [Pubmed]

Schleussner N, Merkel O, Costanza M, Liang HC, Hummel F, Romagnani C, Durek P, Anagnostopoulos I, Hummel M, Jöhrens K, Niedobitek A, Griffin PR, Piva R, Sczakiel HL, Woessmann W, Damm-Welk C, Hinze C, Stoiber D, Gillissen B, Turner SD, Kaergel E, von Hoff L, Grau M, Lenz G, Dörken B, Scheidereit C, Kenner L, Janz M, Mathas S. The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma. Leukemia 32:1994-2007 (2018). [Pubmed]

Buckley MA, Woods NT, Tyrer JP, Mendoza-Fandiño G, Lawrenson K, Hazelett DJ, Najafabadi HS, Gjyshi A, Carvalho RS, Lyra PC Jr, Coetzee SG, Shen HC, Yang AW, Earp MA, Yoder SJ, Risch H, Chenevix-Trench G, Ramus SJ, Phelan CM, Coetzee GA, Noushmehr H, Hughes TR, Sellers TA, Goode EL, Pharoah PD, Gayther SA, Monteiro ANA; Ovarian Cancer Association Consortium. Functional Analysis and Fine Mapping of the 9p22. 2 Ovarian Cancer Susceptibility Locus 79:467-481 (Cancer). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.