Transcription Factor
| Accessions: | Q6ZN30 (JASPAR 2024) |
| Names: | BNC2_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q6ZN30 |
| Length: | 1099 |
| Pfam Domains: | 442-461 Zinc-finger of C2H2 type 834-856 C2H2-type zinc finger 1036-1058 Zinc finger, C2H2 type 1037-1058 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MAHLGPTPPPHSLNYKSEDRLSEQDWPAYFKVPCCGVDTSQIESEEAEVDVRERETQRDR 60 61 EPKRARDLTLRDSCTDNSMQFGTRTTTAEPGFMGTWQNADTNLLFRMSQQAIRCTLVNCT 120 121 CECFQPGKINLRTCDQCKHGWVAHALDKLSTQHLYHPTQVEIVQSNVVFDISSLMLYGTQ 180 181 AVPVRLKILLDRLFSVLKQEEVLHILHGLGWTLRDYVRGYILQDAAGKVLDRWAIMSREE 240 241 EIITLQQFLRFGETKSIVELMAIQEKEGQAVAVPSSKTDSDIRTFIESNNRTRSPSLLAH 300 301 LENSNPSSIHHFENIPNSLAFLLPFQYINPVSAPLLGLPPNGLLLEQPGLRLREPSLSTQ 360 361 NEYNESSESEVSPTPYKNDQTPNRNALTSITNVEPKTEPACVSPIQNSAPVSDLTKTEHP 420 421 KSSFRIHRMRRMGSASRKGRVFCNACGKTFYDKGTLKIHYNAVHLKIKHRCTIEGCNMVF 480 481 SSLRSRNRHSANPNPRLHMPMLRNNRDKDLIRATSGAATPVIASTKSNLALTSPGRPPMG 540 541 FTTPPLDPVLQNPLPSQLVFSGLKTVQPVPPFYRSLLTPGEMVSPPTSLPTSPIIPTSGT 600 601 IEQHPPPPSEPVVPAVMMATHEPSADLAPKKKPRKSSMPVKIEKEIIDTADEFDDEDDDP 660 661 NDGGAVVNDMSHDNHCHSQEEMSPGMSVKDFSKHNRTRCISRTEIRRADSMTSEDQEPER 720 721 DYENESESSEPKLGEESMEGDEHIHSEVSEKVLMNSERPDENHSEPSHQDVIKVKEEFTD 780 781 PTYDMFYMSQYGLYNGGGASMAALHESFTSSLNYGSPQKFSPEGDLCSSPDPKICYVCKK 840 841 SFKSSYSVKLHYRNVHLKEMHVCTVAGCNAAFPSRRSRDRHSANINLHRKLLTKELDDMG 900 901 LDSSQPSLSKDLRDEFLVKIYGAQHPMGLDVREDASSPAGTEDSHLNGYGRGMAEDYMVL 960 961 DLSTTSSLQSSSSIHSSRESDAGSDEGILLDDIDGASDSGESAHKAEAPALPGSLGAEVS 1020 1021 GSLMFSSLSGSNGGIMCNICHKMYSNKGTLRVHYKTVHLREMHKCKVPGCNMMFSSVRSR 1080 1081 NRHSQNPNLHKNIPFTSVD |
| Interface Residues: | 419, 422, 426, 428, 429, 432, 438, 451, 452, 453, 454, 455, 456, 458, 459, 481, 482, 484, 485, 486, 488, 489, 1045, 1046, 1047, 1048, 1049, 1051, 1052, 1076, 1077, 1078, 1079, 1080, 1081, 1082 |
| 3D-footprint Homologues: | 7y3l_A, 7y3m_I, 8cuc_F, 5yel_A, 1ubd_C, 6jnm_A, 6wmi_A, 4m9v_C, 1tf6_A, 5yj3_D, 1g2f_F, 2drp_D, 6e94_A, 7txc_E, 2wbs_A |
| Binding Motifs: | MA1928.1 wwrTGAGTCAyw MA1928.2 TGAGTCA |
| Binding Sites: | MA1928.2.16 MA1928.2.11 MA1928.2.19 MA1928.2.5 MA1928.2.12 / MA1928.2.13 / MA1928.2.14 / MA1928.2.18 / MA1928.2.2 / MA1928.2.9 MA1928.2.1 / MA1928.2.8 MA1928.2.3 MA1928.1.1 / MA1928.1.4 MA1928.1.10 / MA1928.1.16 MA1928.1.11 / MA1928.1.18 MA1928.1.12 / MA1928.1.20 MA1928.1.13 MA1928.1.14 MA1928.1.15 MA1928.1.16 MA1928.1.17 MA1928.1.18 MA1928.1.19 MA1928.1.2 / MA1928.1.5 MA1928.1.20 MA1928.1.3 / MA1928.1.7 MA1928.1.4 MA1928.1.5 / MA1928.1.8 MA1928.1.10 / MA1928.1.6 MA1928.1.12 / MA1928.1.7 MA1928.1.13 / MA1928.1.8 MA1928.1.14 / MA1928.1.9 MA1928.2.17 / MA1928.2.7 MA1928.1.1 MA1928.1.11 MA1928.1.15 MA1928.1.17 MA1928.1.19 MA1928.1.2 MA1928.1.3 MA1928.1.6 MA1928.1.9 MA1928.2.10 / MA1928.2.20 MA1928.2.15 MA1928.2.4 MA1928.2.6 |
| Publications: | Buckley MA, Woods NT, Tyrer JP, Mendoza-Fandiño G, Lawrenson K, Hazelett DJ, Najafabadi HS, Gjyshi A, Carvalho RS, Lyra PC Jr, Coetzee SG, Shen HC, Yang AW, Earp MA, Yoder SJ, Risch H, Chenevix-Trench G, Ramus SJ, Phelan CM, Coetzee GA, Noushmehr H, Hughes TR, Sellers TA, Goode EL, Pharoah PD, Gayther SA, Monteiro ANA; Ovarian Cancer Association Consortium. Functional Analysis and Fine Mapping of the 9p22. 2 Ovarian Cancer Susceptibility Locus 79:467-481 (Cancer). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.