DNA Binding Site

Accessions: 6byy_E (3D-footprint 20231221), 6bz1_E (3D-footprint 20231221), 6bz1_G (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 13
Sequence: ACTATTTATAAGA
Type: Heterodimer
Binding TFs: 6byy_D (SRF-type transcription factor (DNA-binding and dimerisation domain))
6bz1_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
6bz1_D (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Motifs: 6bz1_CD cTAnnnntAA
6byy_CD TTnnnnnkAs
6bz1_AB CTtnnnnaTa
Publications: Lei X, Kou Y, Fu Y, Rajashekar N, Shi H, Wu F, Xu J, Luo Y, Chen L. The Cancer Mutation D83V Induces an α-Helix to β-Strand Conformation Switch in MEF2B. J Mol Biol 430:1157-1172 (2018). [Pubmed]

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