DNA Binding Motif

Accessions: 6byy_CD (3D-footprint 20231221)
Names: MEF2 CHIMERA
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: MEF2 CHIMERA/DNA Complex
Length: 10
Consensus: TTnnnnnkAs
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 0 0 0 96 T
03 24 24 24 24 n
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 13 13 29 41 k
09 96 0 0 0 A
10 13 27 54 2 s
Type: Heterodimer
Binding TFs: 6byy_C (SRF-type transcription factor (DNA-binding and dimerisation domain))
6byy_D (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 6byy_E
6byy_F
Publications: Lei X, Kou Y, Fu Y, Rajashekar N, Shi H, Wu F, Xu J, Luo Y, Chen L. The Cancer Mutation D83V Induces an α-Helix to β-Strand Conformation Switch in MEF2B. J Mol Biol 430:1157-1172 (2018). [Pubmed]

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