DNA Binding Site

Accessions: 2xro_Y (3D-footprint 20231221)
Organisms: Pseudomonas putida, strain DOT-T1E
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 42
Sequence: GCTGAATCGTAATGCGGTAGAGTGTAGCATTATGTGATACTC
Type: Heterodimer
Binding TFs: 2xro_E (Bacterial transcriptional regulator, Transcriptional regulator, IclR helix-turn-helix domain, Winged helix-turn-helix DNA-binding)
2xro_F (Bacterial transcriptional regulator, Transcriptional regulator, IclR helix-turn-helix domain, Winged helix-turn-helix DNA-binding)
Binding Motifs: 2xro_ABEF TnTCAnnnnnTGCTAnnnnnTACCGnnnnnCGAnT
2xro_E CGgtA
Publications: Lu D, Fillet S, Meng C, Alguel Y, Kloppsteck P, Bergeron J, Krell T, Gallegos M.T, Ramos J, Zhang X. Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators. Genes & development 24:2556-65 (2010). [Pubmed]

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