Transcription Factor

						

			
Accessions: 2xro_A (3D-footprint 20231221), 2xro_E (3D-footprint 20231221)

			
Names: HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV, Toluene tolerance pump ttgGHI operon repressor, TTGV_PSEPT
Organisms: Pseudomonas putida, strain DOT-T1E
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q93PU6
Length: 239
Pfam Domains:      3-50 IclR helix-turn-helix domain
     6-61 Transcriptional regulator
     9-46 Winged helix-turn-helix DNA-binding
  115-218 Bacterial transcriptional regulator
Sequence: 
(in bold interface residues)		   1 QVIARAASIMRALGSHPHGLSLAAIAQLVGLPRSTVQRIINALEEEFLVEALGPAGGFRL   60
  61 GPALGQLINQAQTDILSLVKPYLRSLAEELDESVSLASLAGDKIYVLDRIVSERELRVVF  120
 121 PIGINVPAAATAAGKVLLAALPDETLQAALGEQLPVLTSNTLGRKALVKQLSEVRQSGVA  180
 181 SDLDEHIDGVSSFATLLDTYLGYYSLAIVMPSSRASKQSDLIKKALLQSKLNIERAIGR
Interface Residues: 22, 32, 33, 34, 35, 37, 38
3D-footprint Homologues: 2xro_E, 3iyd_H
Binding Motifs: 2xro_ABEF TnTCAnnnnnTGCTAnnnnnTACCGnnnnnCGAnT
2xro_E CGgtA
Binding Sites: 2xro_X
2xro_Y
			
Publications: Lu D, Fillet S, Meng C, Alguel Y, Kloppsteck P, Bergeron J, Krell T, Gallegos M.T, Ramos J, Zhang X. Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators. Genes & development 24:2556-65 (2010). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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