Transcription Factor
| Accessions: | 2xro_B (3D-footprint 20231221), 2xro_F (3D-footprint 20231221) |
| Names: | HTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV, Toluene tolerance pump ttgGHI operon repressor, TTGV_PSEPT |
| Organisms: | Pseudomonas putida, strain DOT-T1E |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q93PU6 |
| Length: | 240 |
| Pfam Domains: | 4-51 IclR helix-turn-helix domain 7-62 Transcriptional regulator 10-47 Winged helix-turn-helix DNA-binding 116-219 Bacterial transcriptional regulator |
| Sequence: (in bold interface residues) | 1 IQVIARAASIMRALGSHPHGLSLAAIAQLVGLPRSTVQRIINALEEEFLVEALGPAGGFR 60 61 LGPALGQLINQAQTDILSLVKPYLRSLAEELDESVSLASLAGDKIYVLDRIVSERELRVV 120 121 FPIGINVPAAATAAGKVLLAALPDETLQAALGEQLPVLTSNTLGRKALVKQLSEVRQSGV 180 181 ASDLDEHIDGVSSFATLLDTYLGYYSLAIVMPSSRASKQSDLIKKALLQSKLNIERAIGR 240 |
| Interface Residues: | 23, 33, 34, 35, 36, 38, 39 |
| 3D-footprint Homologues: | 2xro_E, 3iyd_H |
| Binding Motifs: | 2xro_ABEF TnTCAnnnnnTGCTAnnnnnTACCGnnnnnCGAnT |
| Binding Sites: | 2xro_X 2xro_Y |
| Publications: | Lu D, Fillet S, Meng C, Alguel Y, Kloppsteck P, Bergeron J, Krell T, Gallegos M.T, Ramos J, Zhang X. Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators. Genes & development 24:2556-65 (2010). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.