DNA Binding Motif

Accessions: GCM2_DLX3_1 (HumanTF2 1.0)
Names: GCM2_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: aTrcGGGywkwyttAATtr
Weblogo:
PSSM: P0 A C G T
01 2925 671 1195 163 a
02 75 305 133 4120 T
03 1338 206 2782 0 r
04 1320 4120 1341 836 c
05 437 36 4120 361 G
06 0 24 4120 6 G
07 0 26 4120 59 G
08 621 1275 347 1877 y
09 1271 904 825 1120 w
10 968 812 1088 1253 k
11 1283 766 875 1196 w
12 893 1114 1019 1094 y
13 925 709 1008 1479 t
14 1109 763 359 4120 t
15 4120 354 647 586 A
16 4120 32 232 429 A
17 511 467 793 4120 T
18 844 534 937 3183 t
19 1959 437 2161 861 r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
GCM2_TF1 (GCM motif protein)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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