DNA Binding Motif

						

			
Accessions: TFAP2C_ONECUT2_2_3 (HumanTF2 1.0)

			
Names: TFAP2C_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 26
Consensus: tATCGAyyggwyrtysCCysrGGsga
Weblogo: 
PSSM: P0      A      C      G      T
01    292    221    183    619      t
02   1315      0    115     88      A
03     55      9      0   1315      T
04     34   1315      8    372      C
05     90     18   1315     32      G
06   1315      0      0     56      A
07     33    613      0   1315      y
08    186    583    177    368      y
09    237    298    556    224      g
10    315    301    405    294      g
11    411    179    320    406      w
12    231    389    267    428      y
13    371    214    467    263      r
14    273    196    238    608      t
15    302    400    204    408      y
16    191    821   1315     95      s
17      8   1315     13      0      C
18      8   1315     17    181      C
19    114    655    494   1315      y
20    310    334    477    194      s
21    732    206    333     44      r
22    392     34   1315     15      G
23     13      0   1315      0      G
24     31    802    513     79      s
25    314    286    401    314      g
26    481    292    232    311      a
Type: Heterodimer
Binding TFs: ONECUT2_TF2 (Homeobox domain, CUT domain)
TFAP2C_TF1 (Transcription factor AP-2)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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