DNA Binding Motif

Accessions: 4zpk_AB (3D-footprint 20231221)
Names: Aryl hydrocarbon receptor nuclear translocator
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of the Heterodimeric HIF-2a:ARNT Complex with HRE DNA
Length: 7
Consensus: ACGTGCG
Weblogo:
PSSM: P0 A C G T
01 73 7 9 7 A
02 0 96 0 0 C
03 0 0 96 0 G
04 0 0 0 96 T
05 7 7 75 7 G
06 7 73 9 7 C
07 9 7 73 7 G
Type: Heterodimer
Binding TFs: 4zpk_A (Helix-loop-helix DNA-binding domain, PAS fold, PAS fold, PAS domain)
4zpk_B (PAS fold, PAS fold, PAS domain)
Binding Sites: 4zpk_C
4zpk_D
Publications: Wu D, Potluri N, Lu J, Kim Y, Rastinejad F. Structural integration in hypoxia-inducible factors. Nature 524:303-8 (2015). [Pubmed]

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